Mealtime insulin has an INsulin and OUTsulin component
Mealtime insulin has a quick onset
The medical professionals who guide your diabetes treatment may prescribe mealtime insulin. With good reason: It helps control high blood sugar. Mealtime insulin can help lower blood sugar spikes that can happen when you eat, helping you reach and maintain your A1C goal. But it’s also very important to understand when mealtime insulin leaves the body.
Mealtime INsulin also has an OUTsulin part
Rapid acting AFREZZA is a mealtime insulin that is breathed in through the mouth with an inhaler to help control mealtime blood sugar spikes and lower A1C. When taken at the beginning of a meal, safe and effective AFREZZA insulin offers fast absorption into the body through the lungs. It goes to work quickly to act on your meal, starting to work in approximately 12 minutes. It reaches its peak around 35-45 minutes1.
But what about when your body no longer needs insulin for that meal? After you take AFREZZA, your blood sugar returns to near pre-meal levels in approximately 90 to 180 minutes1. That’s when you can appreciate the OUTsulin side of AFREZZA: INsulin that does its job and then leaves.
AFREZZA® helps control blood sugar spikes at mealtime
AFREZZA should not be taken if you have problems with your lungs such as COPD (chronic obstructive pulmonary disease) or asthma. Before initiating AFREZZA, your doctor will perform a detailed medical history, physical examination, and a breathing test (called spirometry) to check how your lungs are working before you begin to use AFREZZA. To find out if AFREZZA is right for you, talk to your healthcare professional.
Controlling your after-meal blood sugar levels (PPG) is important to A1C control2
When you eat, your blood sugar spikes; and with 3 meals daily, this can result in increasing blood sugar levels throughout the day. These blood sugar spikes have an effect on your A1C, which is a measure of your blood sugar control over the past 3 months. Your A1C is made up of both FPG, which is your fasting (not eating) blood sugar and your after-meal glucose levels, also known as post-prandial glucose or PPG.
The closer you get to your A1C goal, your PPG plays an even more important role. Your healthcare provider may add a mealtime insulin, or rapid acting insulin, like AFREZZA, to your diabetes treatment plan, to help you reduce your mealtime blood sugar levels.
AFREZZA® starts working in approximately 12 minutes
When you’re ready for your meal, inhale your AFREZZA insulin and begin eating. AFREZZA can then help control the after-meal blood sugar spikes that affect your A1C.2
Based on a study of 30 adults with Type 1 diabetes after taking a single dose of 4 and 12 units of AFREZZA. A 48 unit dose showed a time to first measurable effect of ~12 minutes, time to peak effect of ~55 minutes and time for effect to return to baseline of ~4.5 hours.
AFREZZA offers a range of insulin dosing options—including 4, 8 and 12-unit cartridges—to help you with your meal planning and after-meal blood sugar control. To find out if AFREZZA may be a mealtime insulin option for you, talk to your healthcare professional.
Remember to monitor your blood sugar levels
While using AFREZZA, it’s important to test your blood sugar levels as recommended by your healthcare professional. You can use our downloadable blood sugar log to help keep track of your blood sugar levels. It’s important to share the results with your healthcare professional, who can help determine how well your treatment program is working for you.
* for the 4 and 12 unit cartridges respectively
1. Afrezza Prescribing Information
2. Monnier L, Colette C. Contributions of fasting and postprandial glucose to hemoglobin A1c. Endocr Pract. 2006;12(Suppl 1):42-46.