Mealtime insulin has an INsulin and OUTsulin component
Mealtime insulin has a quick onset
The medical professionals who guide your diabetes treatment may prescribe mealtime insulin. With good reason: It helps control high blood sugar.
They often focus on how quickly it handles your food intake to lower blood sugar spikes that can happen when you eat, helping you reach and maintain your hemoglobin A1C goal. It’s time for another discussion: how mealtime INsulin leaves the body, which you can think of as OUTsulin.
Mealtime INsulin also has an OUTsulin part
Rapid-acting AFREZZA is a mealtime insulin that is breathed in through the mouth with an inhaler to help control mealtime blood sugar spikes and lower A1C. When taken at the beginning of a meal, safe and effective AFREZZA insulin offers fast absorption into the body through the lungs. It goes to work quickly, reaching maximum effect in approximately 53 minutes and can stay active for up to 3 hours.
Three hours after you take AFREZZA your blood sugar returns to near pre-meal levels. That’s why you can appreciate the OUTsulin side of AFREZZA: INsulin that does its job and then leaves.
AFREZZA® helps control blood sugar spikes at mealtime
AFREZZA should not be taken if you have problems with your lungs such as COPD (chronic obstructive pulmonary disease) or asthma. Before initiating AFREZZA, your doctor will perform a detailed medical history, physical examination, and a breathing test (called spirometry) to identify potential lung problems. To find out if AFREZZA is right for you, talk to your healthcare professional.
Controlling your after-meal blood sugar levels (PPG) is important to A1C control
When you eat, your blood sugar spikes; and with 3 meals daily, this can result in increasing blood sugar levels throughout the day. These blood sugar spikes have an effect on your A1C, which is a measure of your blood sugar control over the past 2 to 3 months. Your A1C is made up of both FPG, which is your fasting (not eating) blood sugar and your PPG, which is your after-meal blood sugar.
The closer you get to your A1C goal, your PPG plays an even more important role. Your healthcare professional may add a mealtime insulin, or rapid-acting insulin, like AFREZZA, to your diabetes treatment plan, to help you reduce your mealtime blood sugar levels.
AFREZZA® reaches maximum (peak) level in 12 to 15 minutes
When you’re ready for your meal, use the specially designed inhaler to inhale your AFREZZA insulin, and then begin eating. AFREZZA can then help control your after-meal blood sugar spikes that affect your A1C. In a study of 12 patients, the maximum (peak) level of insulin was reached in 12 to 15 minutes.
Despite the faster absorption of insulin from AFREZZA, the onset of activity was comparable to insulin lispro.
AFREZZA offers a range of insulin dosing options—including 4-, 8- and 12-unit cartridges—to help you with your meal planning and after-meal blood sugar control. To find out if AFREZZA may be a mealtime insulin option for you, talk to your healthcare professional.
Remember to monitor your blood sugar levels
While using AFREZZA, it’s important to test your blood sugar levels as recommended by your healthcare professional. You can use our downloadable blood sugar log to help keep track of your blood sugar levels. It’s important to share the results with your healthcare professional, who can help determine how well your treatment program is working for you.